Domestic

In the U.S., 21 Clinical Research Consortium for Spinocerebellar Ataxia institutions will participate in Aim 1 of this study. Those include:

*Houston Methodist is the coordinating site for the study.

The University of Minnesota, Johns Hopkins University, Massachusetts General Hospital/Harvard Medical School, and the University of Florida will conduct Magnetic Resonance Imaging/MRS studies of Aim 2.

International

The European Ataxia Study Group (EASG) is the major European multinational consortium formed to conduct clinical research on ataxia. EASG comprises more than 50 ataxia investigators from institutions across Europe and even a few in northern Africa. The University Hospital of Bonn Bonn, Germany and the Brain & Spine Institute at the Hôpital Pitié Salpêtrière in Paris, France will serve as the lead coordinating centers for the European institutions and will conduct the Magnetic Resonance Imaging/MRS studies of Aim 2 in Europe. They will receive referrals from all European investigators.