Domestic

In the U.S., 21 Clinical Research Consortium for Spinocerebellar Ataxia institutions will participate in Aim 1 of this study. Those include:

Columbia University

Emory University

Houston Methodist Research Institute*

Johns Hopkins University

Harvard University/Massachusetts General Hospital

Northwestern University

Ohio State University

Stanford University

University of Alabama Birmingham

University of California Los Angeles

University of California San Francisco

University of Colorado

University of Chicago

University of Florida

University of Iowa

University of Michigan

University of Minnesota

University of Rochester Medical Center

University of Texas Southwestern Medical Center

University of South Florida

*Houston Methodist is the headquarters site for the study.

The University of Minnesota, Johns Hopkins University, Massachusetts General Hospital/Harvard Medical School, and the University of Florida will conduct Magnetic Resonance Imaging/MRS studies of Aim 2.

International

Dr. Thomas Klockgether of the German Center for Neurodegenerative Diseases (DZNE), University Hospital of Bonn, Bonn, Germany leads the European Ataxia Study Group (EASG), the European multinational consortium comprising more than 50 ataxia investigators from institutions across Europe and even a few in northern Africa. The EASG has conducted studies such as EUROSCA, RISCA and ESMI.

Dr. Alexandra Durr of the Brain & Spine Institute (ICM), the Hôpital Pitié Salpêtrière in Paris, France leads the SPATAX network of 28 European investigators to conduct clinical and genetic analysis of cerebellar ataxias and spastic paraplegias.